Discrepancies in Xpert tuberculosis testing
نویسندگان
چکیده
منابع مشابه
Impact of Xpert MTB/RIF Testing on Tuberculosis Management and Outcomes in Hospitalized Patients in Uganda
RATIONALE The clinical impact of Xpert MTB/RIF for tuberculosis (TB) diagnosis in high HIV-prevalence settings is unknown. OBJECTIVE To determine the diagnostic accuracy and impact of Xpert MTB/RIF among high-risk TB suspects. METHODS WE PROSPECTIVELY ENROLLED CONSECUTIVE, HOSPITALIZED, UGANDAN TB SUSPECTS IN TWO PHASES: baseline phase in which Xpert MTB/RIF results were not reported to cli...
متن کاملXpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children
In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children.
متن کاملXpert MTB/RIF testing in a low tuberculosis incidence, high-resource setting: limitations in accuracy and clinical impact.
BACKGROUND Xpert MTB/RIF, the first automated molecular test for tuberculosis, is transforming the diagnostic landscape in low-income countries. However, little information is available on its performance in low-incidence, high-resource countries. METHODS We evaluated the accuracy of Xpert in a university hospital tuberculosis clinic in Montreal, Canada, for the detection of pulmonary tubercu...
متن کاملEarly tuberculosis treatment monitoring by Xpert(R) MTB/RIF.
Vilnius, Lithuanian National Tuberculosis Control Programme, 2011. 3 Bakonyte D, Baranauskaite A, Cicenaite J, et al. Molecular characterization of isoniazid-resistant Mycobacterium tuberculosis clinical isolates in Lithuania. Antimicrob Agents Chemother 2003; 47: 2009–2011. 4 Kliiman K, Altraja A. Predictors of extensively drug-resistant pulmonary tuberculosis. Ann Intern Med 2009; 150: 766–77...
متن کاملThe Feasibility of Xpert MTB/RIF Testing to Detect Rifampicin Resistance among Childhood Tuberculosis for Prevalence Surveys in Northern China
Drug resistance surveillance is crucial for control of drug-resistant tuberculosis (TB). However, limited data exists on the burden of drug-resistant TB in children. The goal of this work was to generate prevalence data regarding rifampicin- (RIF-) resistant childhood TB in northern China and to test the feasibility of Xpert for surveying pediatric TB drug resistance prevalence. We enrolled 362...
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ژورنال
عنوان ژورنال: The Lancet Microbe
سال: 2020
ISSN: 2666-5247
DOI: 10.1016/s2666-5247(20)30033-1